LOCI Bio-Formats plugins for ImageJ The Laboratory for Optical and Computational Instrumentation (LOCI) is a biophotonics instrumentation laboratory with a mission is to develop advanced optical and computational techniques for imaging and experimentally manipulating living specimens. Bio-Formats is a standalone Java library for reading and writing life sciences image file formats. It is capable of parsing both pixels and metadata for a large number of formats, as well as writing to several formats. This is the LOCI tools complete bundle and contains everything needed to read images into ImageJ using Bio-Formats.